Friday, February 28, 2025

Female Reproductive organs: Human

Female reproductive organs are ovaries, oviducts, uterus vagina, External genitalia , mammary glands and accessory glands.

This system is Concerned with formation of ova, fertilization, foetal development and child birth.

ovaries: Are primary sex organs of female. A pair of ovaries are present in pelvic Cavity each on either side of uterus. Each ovary is Small sized (3 cm x 2 cm X 1 cm) & almond Shaped structure.



ovary remains attached with dorsal body wall by mesovarium while with pelvic wall (lateral) by suspensory ligament and with uterus by Ovarian ligament.



Each ovary is solid internally and remains lined by germinal epithelium ( now called surface epithelium) of Cuboidal epithelial cells. Inner to surface epithelium tunica albuginea , a layer of fibrous connective tissue is present. Inner to it, the stroma or matrix of ovary is present which remains differentiated into outer Cortex and inner medulla.

 The Cortex Contains a number of Small, oval or rounded

 developing ovarian or primary follicles in different stages of

 development. From puberty, every month one of the follicle

 Charges into Graffian follicle under the influence of FSH. The

 graafian follicle produces hormone estrogen. The graffian follicle

 Contains secondary oocyte and by ovulation it forms ovum. The

 remaining structures of graffian follicle forms


Corpus luteum which acts as temporary endocrine gland and produces hormone progesterone. If egg do not get fertilized,  the Corpus luteum degenerates into corpus albicans.

The medulla is less dense and Contains blood vessels, nerves, connective tissue etc.

The part of ovary through which blood vessels and nerves enter/leave ovary is called hilum.



 

Fallopian tubes or oviducts: 1 pair, long (10cm), Ciliated , muscular and tubular structure extending from ovary to uterus. It remains suspended by mesosalpinx (peritoneum). Each oviduct has 3 parts:

Infundibulum: It lies near ovary and it's opening is called ostium which remains surrounded by fine finger like projections called fimbrae which Captures egg during ovulation.

Ampulla: It is outer Curved and widest part. If sperm comes ; fertilization takes place here.

it is also Common site for ectopic pregnancy (Implantation of zygote in other place than uterus).

Isthmus: It is narrow part which opens into uterus.

A small part of oviduct lies inside uterus called uterine part.

Internally , oviduct remains lined by Ciliated Columnar epithelium (for the movement of ovum) and non-ciliated glandular (secretory Cells) Called peg cells provide nutrients to ovum , zygote and sperms. They also help in Capacitation of sperm.

Functions: to carry egg , act as site of fertilization and provide nutrients to ovum, sperm and zygote.


 Uterus or womb or Hystera: It is large ( 8cm X 5cm x 2cm) , hollow,

 muscular, highly vascular and inverted pear shaped structure

 where growth of embryo takes place. It lies in pelvic Cavity in

 between urinary bladder and rectum. It remains suspended by

 mesometrium.

It Consists of 3 parts: Fundus, Body and Cervix.

Fundus: is upper dome shaped structure lies above the opening of oviducts. It is the Common site of implantation.

corpus: is main two-third part also called body.

Cervix: is lower one-third tubular part and Consists of outer ectocervix and inner endocervix with inner Cervical Canal which contains thick mucus produced by cells which lines it. The endocervix opens into corpus  of uterus by internal OS while ectocervix opens into Vagina by

external Os. The endocervix remains lined by columnar epithelial cells while ectocervix remains lined by squamous epithelial cells and the area where they meet is Called transitional or transformation Zone which is most common site for Cervical cancer ( Caused by Human papilloma virus - HPV).

Pap smear test is done to diagnose cervical Cancer.


 The wall of uterus consists of 3 layers:

perimeterium, myometrium and endometrium.

⇒ perimeterium: also called epimetrium is outer layer and consists of simple squamous epithelial Cells.

myometrium: is middle , thickest layer of smooth muscles.

Endometrium: is innermost layer and remains lined by Columnar epithelial Cells. It Consists of two layers: stratum


basilis or basilar layer towards myometrium and stratum functionalis (functional layer). The functional layer changes during menstrual cycle.

* surgical removal of Uterus is called Hysterectomy.

uterine prolaps (Aang Khasnu) : uterus slips off from its position into vagina and is Common among multiparous ( having many births) woman.

* uterine - cervical cancer (common among multiparous) is most common among Neplease woman while Breast cancer (common among Nulliparous) is most common among woman of world.

vagina: It is a muscular tubular structure extending from Cervix to outside. It is about 8-10 cm in length and remains lined by non-keratinised stratified squamous epithelium. It's inner surface has transverse folds Called vaginal rugae. The PH of vagina is about (4-4.5) due to bacteria Lactobacillus acidophilus which produces lactic acid to inhibit growth of other micro organisms.

It opens into vestibule by vaginal orifice partially Covered by a thin layer of mucus membrane Called hymen.

Generally hymen breaks during first Coitus. However, it may breaks during vigorous physical activity, cycling, Horse riding, Jumping etc.

vagina acts as Copulation Canal as it receives penis /sperm during sexual intercourse , as passage for menstrual flow and as birth canal.




External genitalia or vulva: It consists of following structures:

Mons pubis: It is anterior most part of external genitalia and consists of fatty tissue Covered by Skin and acts as cushion. It contains pubic hairs after puberty.




vestibule: Central depressed plate like structure which contains two openings; urethral orifice (anterior) and vaginal orifice (Posterior).

Labia Minora: vestibule remains bounded by thin , moist and smaller fold of skin with sebaceous gland called as labia minora. posteriorly the labia minora are fused together to form fourchette. Anteriorly they fuse to form prepuce in front of clitoris. The clitoris is small, finger like, erectile and highly sensative organ at the top of vestibule. .

The space between fourchette and anus is Called perineum.


Labia majora: These are two large thick fatty folds of skin  outer to labia minora and forms boundary of vulva. They are partially Covered by pubic hair and Contain many sebaceous glands.

Accessory glands: two type of vestibular glands are present:

Greater vestibular glands: Also called Bartholin's glands are a pair of small , pea-sized gland located each on the either side of vaginal orifice. They secrete alkaline viscous fluid which provides lubrication during sexual intercourse.

Lesser vestibular glands: Also called paraurethral glands or glands of skene: Are numerous minute glands on either side of urethral orifice. They secrete mucus to lubricate the vagina during sexual arousal and also protect from infection.

 

Mammary glands (Breasts): Are rounded eminences located over the pectoralis major muscle on the front wall of thorax (second to sixth Ribs) and remain held by suspensory ligaments called Cooper's ligaments. They enlarge considerably in adult female. Externally, they remain Covered by Skin and Contain small elevated area at middle Called nipple which remains surrounded by a circular , pigmented area called areola. The areola contains sebaceous gland which produces oily secretion to prevent cracking of nipple specially during lactation.

Internally, it contains adipose tissue, Connective tissue and mammary glands.

The amount of fat determines size of breast. The Connective tissue supports mammary glands.






The mammary gland is modified sweat gland, apocrine &

tubulo-alveolar gland.

Each mammary gland Consists of (15-20) lobules of compound tubulo-alveolar gland which secrete milk to nourish the new baby. Each lobule is cluster Cells Called alveolie. The Cells of alveolie produces milk which is stored in the lumen of alveolie. The alveolie open into mammary tubules and these mammary tubules of each lobe Join to form mammary duct. several mammary ducts Join to form a wider mammary ampulla or  lactiferous sinus where milk maybe stored before going to lacticferous duct. Each lactiferous duct opens at the top of nipple and Carries milk from one lobule to exterior.  

In non-pregnant woman , the glandular tissue is scanty.



During pregnancy, glands grow under the influence of oestrogen and progesterone. on infant's birth, prolactin stimulates the Production of milk and oxytocin Causes release of milk as infants sucks the breast.

After menopause, the gland atrophy.

A nursing woman secretes 1 to 2 Itrs milk per day. The first day milk is Called Colostrum & Contains immunoglobins (IgA).

. Rudimentary milk glands are present in male.

Hormones:

Estrogen :  for growth of Growth of breasts.

progesterone: To increase number of alveolie during pregnancy.

prolactin: For milk production.

oxytocin: For ejection of milk.

Homologous organs of male and female reproductive

system